Use the little bookmark-shaped or text bubble icon next to each variant to open the “flagging / comment” window. Check the desired flags and/or enter your comment text in the text box below. Click Save to create a new comment and/or flags.
You can export comments and flags together with your variants into an Excel file.
The comments and flags for a variant are displayed in the variant details. For this, click the arrow at the beginning of a resulting row. The comments and flags are displayed in the box in the top right of the expanded variant details.
Alternatively, you can also view your comments and flags in the case details overview as described below in the “Viewing Annotations” section.
Use the little gray box next to each variant to open the “ACMG Rating” window. Check the desired classifications and click Save to create a ACMG rating. The actual class is automatically computed. You can override the computation and set your own class by entering a number in the Class override box.
You can get a complete list of all the comments, flags and ACMG ratings for a case in the case details view. For this, go back to the case detail page and click on Variant Annotations.